The Institutional Ethics Committee (IEC) (for Human Research) was established in June 2008 at Alagappa University (AU), Karaikudi. The biomedical and health research involving human participants, human biological material, and the associated data are conducted in Alagappa University following the basic and general ethical principles outlined in the revised “National Ethical Guidelines for Biomedical and Health Research Involving Human Participants, 2017” issued by the ICMR, India. The AU IEC reviews the ethics involved in research involving human participants for ongoing projects as well as the ones submitted to various funding agencies, to ensure that experiments involving human participants are conducted in compliance with ICMR, India guidelines. It contributes to the advancement of basic research on human subjects in the field of biological sciences at AU.